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Technology and Equipment

Discovery & Development Formulation

Therapeutic protein products used for the differentiation and characterization of subvisible particulates

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Manufacture Business Practice

Assessing the effect of formulation composition on spidroin charge and stability

Work performed in conjunction with Spiber Technologies, Uppsala, Sweden. Use of dynamic and electrophoretic light scattering to assess the effects of protein formulation composition

Manufacture Drug Delivery

Ready to Break the Mold?

| Sponsored by Schott

Pharma suppliers are teaming up to take ready-to-use technology to the next level.

Discovery & Development Business Practice

Design and formulation of nanomedicines

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Discovery & Development Biosimilars

Taylor Dispersion Analysis explained

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

Discovery & Development Business Practice

Accelerate liquid formulation development for protein biopharmaceuticals

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

Discovery & Development Business Practice

Reverse engineering of a pharmaceutical formulation

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Manufacture Drug Delivery

Aptar Pharma’s Ophthalmic Squeeze Dispenser – Innovation based on experience

| Sponsored by Aptar

Although the discussion about the use of preservatives is still somewhat controversial, clinical evidence suggests that patients benefit from unpreserved eye drops especially in chronic conditions.

Manufacture Technology and Equipment

Layer by Layer

Does the fabrication of nanoparticles and nanocapules sound complex? Don’t worry – layer by layer technology allows for simple fabrication of complicated stuff.

Business & Regulation Business Practice

The CMO Serialization Threat

The serialization deadlines are coming. It may seem an age away, but preparing for serialization is not as straightforward as you may think. Do you really want to get left behind?

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