White Papers

NTA utilizes the properties of both light scattering and Brownian motion in order to obtain the particle size distribution of samples in liquid suspension.

Dr. Adrian Velazquez-Campoy and Dr. Natalia Markova

TOYOPEARL Sulfate-650F cation exchange resin can be used for the removal of aggregates, host cell proteins and leached protein A in a single post Protein A mAb polishing step.

Protein stability analysis technologies for the biopharmaceutical industry

Together the techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance; this article examines their application.

The intention of this whitepaper is to explain how DSC is used to characterize the thermal stability of protein biopharmaceuticals (primarily antibodies) during the selection of drug candidates to advance into development.

This application note describes the measurement of protein mobility using the ZSP. Using the diffusion barrier method and appropriate measurement protocols, the most accurate readings possible are obtained.

This application note describes how the combination of automated image analysis with Raman spectroscopy can deliver component specific particle characterization data for pharmaceutical blends such as topical formulations.

Introducing Morphologically-Directed Raman Spectroscopy

Protein A has become a well-established platform for capturing of monoclonal antibodies and Fc-fusion proteins.