Analytical Science

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Analysis of chlorhexidine drug substance using an Agilent 6545 Accurate Mass Q-TOF System and MassHunter Mass Profiler Software.

Sitting Down With... Diane Paskiet, Director of Scientific Affairs at West Pharmaceutical Services, USA.

Incremental improvements to ultra-high performance liquid chromatography (UHPLC) have failed to deliver the tangible advances that researchers really want. Sometimes, a full overhaul by re-engineering from the bottom-up is the only way to innovate and move the field forward.

A capsule being developed in Ireland aims to contain not medicine, but process analytical technology.

Digesting regulatory guidance is not always easy, but understanding the main points – and then paying attention to the details – will improve your chances of success.

Can R&D organizations really afford to kill off analytical data that could be used for future decision-making?

In-depth analysis of original and new candidate drugs for biosimilars is easier than ever before…

New technologies for extractables and leachables testing of small molecules and biopharmaceuticals.