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Clinical Trials

Discovery & Development Clinical Trials

A Brave New Year

| Stephanie Vine

How do we move on from a sombre start to 2016?

Manufacture Business Practice

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

| Sponsored by Malvern Panalytical

See how thermodynamics can be used to improve your lead optimization process.

Business & Regulation Business Practice

The Realities of a Digital World

Advanced digital technologies are sweeping through the world and changing the way we live our lives and do business.

Manufacture Business Practice

Utilization of kinITC in AFFINImeter

| Sponsored by Malvern Panalytical

This application note describes how and when can kinetic information be retrieved from ITC power curves.

Discovery & Development Clinical Trials

Cancer Complexity

| James Ritchie

Clinical development is outmoded; we are witnessing serious attrition in cancer R&D. Perhaps it’s time to live and die by the mantra: “no biomarker, no trial”.

Discovery & Development Clinical Trials

The Cautious Comeback of Oral Peptides

| David J. Brayden

Despite clinical failures in the 1990s, pharma is (cautiously) ready to try again with oral peptide formulations.

Discovery & Development Clinical Trials

Clinical Trial Clarity

| Charlotte Barker

Drug makers and regulators are taking steps towards transparency, but is it enough?

Manufacture Business Practice

Nanoparticle Tracking Analysis: Principles and Methodology

It is well established that the use of nanotechnology in medicine and more specifically drug delivery is spreading rapidly.

Manufacture Business Practice

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Manufacture Biosimilars

Taylor Dispersion Analysis for assessing the self-association and stability of Insulin

| Sponsored by Malvern Panalytical

Taylor Dispersion measurements are used to monitor self-association and oligomeric state in a variety of buffer conditions.

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