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Drug Delivery

Discovery & Development Business Practice

Use of microcalorimetry and its correlation with Size Exclusion Chromatography for rapid screening of the physical stability of large pharmaceutical proteins in solution

Learn how to use DSC to screen for physical stability of proteins in solution.

Discovery & Development Formulation

The Formulation Complex

| Thomas R. Tice, Firouz Asgarzadeh, Norbert Maurer, and Anthony J. Hickey

Experts discuss the trends and challenges in the development of complex dosage forms.

Discovery & Development Dosage Forms

Swallowability by Design

| Thomas Hein

Tablets are the most common dosage form, but have you considered all of your options?

Manufacture Biosimilars

The optimization and scale-up of high shear granulation

This article explains how an inline probe was used to monitor a granulation at three different scales to confirm that, in each case, the granules produced were the same size, and more importantly produced tablets of identical quality as quantified by hardness.

Discovery & Development Drug Delivery

Follicular Drug Delivery: a Root to Success

| Hanzey Yasar, Sarah Gordon, Brigitta Loretz, Kai Schulze, Carlos A Guzman and Claus-Michael lehr

Can hair follicles and nanotechnology help topical drugs overcome the skin barrier?

Discovery & Development Business Practice

Using Taylor Dispersion Analysis to determine oligomeric state of insulin

In this article, we take an introductory look at how TDA works, the information it provides and its complementary application to other techniques within the drug development workflow. In addition, example case study data will showcase the performance of TDA relative to dynamic light scattering (DLS) for assessment of the impact of a range of parameters on the monomer-dimer-hexamer equilibrium of insulin.

Discovery & Development Biosimilars

Accelerating the development of generic pharmaceuticals

In this article, triple detection SEC and MDRS are considered within the context of characterizing complex drug formulations, with specific case studies and results illustrating their application.

Discovery & Development Business Practice

Gold therapy using dynamic light scattering

This article explains how dynamic light scattering (DLS) can be used to gather particle size distribution data for the successful use of nanosized colloidal gold in drug delivery applications.

Manufacture Business Practice

The Innovation Awards 2016

| Stephanie Vine

Nominations are open for The Medicine Maker 2016 Innovation Awards.

Manufacture Facilities

Nominations for The Power List 2017

| Stephanie Vine

Nominations for the 2017 Power List are now open and will close on February 1, 2017.

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