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Drug Delivery

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 3

| Sponsored by Malvern Panalytical

In Part Three, we cover the basic types of DLS deconvolution algorithms used to extract the intensity weighted particle size distribution from the measured correlogram.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 2

| Sponsored by Malvern Panalytical

In Part Two, we cover the influence of concentration effects and particle interactions on DLS results and provide a roadmap for identifying and distinguishing each type of concentration effect.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 1

| Sponsored by Malvern Panalytical

In Part One, we provide an overview of the key principles of DLS: theory, correlation statistics, deconvolution algorithms, and the intensity to mass transform.

Discovery & Development Drug Delivery

Using Raman Spectroscopy to Understand the Conformational Stability of Protein Therapeutics

| Sponsored by Malvern Panalytical

Use of a novel combination of dynamic light scattering and Raman spectroscopy to elucidate the conformational stability and structure of proteins in biopharmaceutical formulations

Discovery & Development Drug Delivery

Printing Medicines for Express Delivery Through the Cheek

Javier Morales tells us why he is investigating inkjet printing for the development of buccal films for the delivery of biologic drugs.

Manufacture Business Practice

Characterization of IgG monomers & their aggregates

| Sponsored by Malvern Panalytical

Two antibody samples were characterized using column calibration and multi-detection SEC, and the results compared...

Manufacture Business Practice

Utilization of kinITC in AFFINImeter

| Sponsored by Malvern Panalytical

This application note describes how and when can kinetic information be retrieved from ITC power curves.

Discovery & Development Drug Delivery

The Medicine Monitor

A digital pill submitted for regulatory approval tells caregivers if you’ve taken your medicine

Business & Regulation Business Practice

Studying low-affinity fragments of ligands by ITC

Dissecting a ligand into smaller fragments can provide a strategy for analyzing the role of key functional groups in a protein-ligand interaction.

Manufacture Business Practice

Nanoparticle Tracking Analysis: Principles and Methodology

It is well established that the use of nanotechnology in medicine and more specifically drug delivery is spreading rapidly.

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