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Drug Delivery

Manufacture Business Practice

Using Differential Scanning Calorimetry (DSC) to optimize antibody manufacturing

| Sponsored by Malvern Panalytical

In this white paper, we report the use of the thermal stability data obtained from DSC to screen conditions for viral inactivation of an antibody1.

Manufacture Business Practice

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

| Sponsored by Malvern Panalytical

See how thermodynamics can be used to improve your lead optimization process.

Manufacture Business Practice

Targeting protein/protein interactions in drug design

Protein interactions define a large fraction of the validated targets for drug development including cancer, diabetes, infection and autoimmune diseases.

Discovery & Development Drug Delivery

Sparking Innovation in Drug Delivery

| Richard N. Dalby

In an industry as diverse as pharmaceuticals, there is much that different disciplines can learn from each another.

Discovery & Development Drug Delivery

A Soluble Solution for Drug Delivery

| Stephanie Vine

Could an ionic liquid–drug system help solve drug insolubility?

Manufacture Drug Delivery

Drugs in Disguise

How to dress drugs to help them survive in the bloodstream.

Manufacture Drug Delivery

Plant Protein Potential

| Stephanie Vine

Can lettuce really help biopharmaceuticals turn over a new leaf? Researchers certainly think so.

Discovery & Development Business Practice

Application of microcalorimetry in drug discovery at Exelixis

In this report, we illustrate the utility of calorimetry in making better laboratory decisions.

Discovery & Development Business Practice

The application of MicroCal VP Capillary DSC at a contract development organization

A case study involving the formulation development of a monoclonal antibody is presented to detail the utility and potential limitations of DSC in support of preformulation for a variety of protein products.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 4

| Sponsored by Malvern Panalytical

In Part Four, we address frequently asked questions related to the application of DLS to the characterization of protein therapeutic formulations.

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