Formulation

Hot Melt Extrusion helps to enable pharmaceutical companies to literally solve their solubilization issue.

Researchers working to gain greater knowledge into crystallization believe that functionalized glass can trigger nucleation of specific crystals.

Functionalized glass is shown to trigger nucleation of specific crystal forms

This application note explores the use of the Morphologi G3-ID for Morphologically-Directed Raman spectroscopy (MDRS) to identify and analyze contaminants including protein aggregates present in a stressed sample of lysozyme, and to compare particles held in suspension within a thin path wet cell with those collected on a filter membrane.

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Work performed in conjunction with Spiber Technologies, Uppsala, Sweden. Use of dynamic and electrophoretic light scattering to assess the effects of protein formulation composition

Industry is beginning to appreciate how formulation microstructure makes a fundamental contribution to dermal drug delivery – and this new understanding emphasizes the key role of excipients.

Solubility is a key for drug delivery but pipelines are full of compounds with poor solubility.

The stability of drug formulations is essential. But what should be monitored – and how often?

3D printing is starting to sound attractive - but we really need to understand our powders.