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February 2016 Issue of The Medicine Maker

Welcome to the February issue of The Medicine Maker! Gurus in this month’s cover feature explain the benefits and successes of transdermal drug delivery systems, while In My View covers subjects such as powder characterization in 3D printing; the dangers of poor translation in drug labels, and why needle-based is not disappearing anytime soon. In Departments, Stephen Colgan from Pfizer talks lean stability, and Shai Mulinari discusses the business of whistle blowers.

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Articles featured in this issue

Business & Regulation Business Practice

Heroes of Medicine Making

| Stephanie Vine

Power List: Last year many nominated business leaders, but did we miss any important unsung heroes?

Discovery & Development Drug Delivery

Why We Like Virus-Like Particles

Could Hepatitis E breathe new life into old drugs in the fight against cancer?

Manufacture Small Molecules

Suspended Amination

Chemists solve a 46-year- old problem to develop a new drug modification method.

Manufacture Standards & Regulation

Competition Crackdown

The UK Competition and Markets Authority (CMA) has handed out a £37.6 million fine to GSK for paying out “value transfers totaling over 50 million pounds” to competitors between 2001 and 2004 to delay the introduction of generic versions of its branded anti-depressant drug, Seroxat (paroxetine).

Business & Regulation Business Practice

Fighting Falsifiers

The EU takes the fight to the falsifiers with a new plan to implement packaging safety features.

Business & Regulation Business Practice

Distraction Tactics

Documents reveal that Turing and Valeant both used PR to divert attention from drug price hikes

Discovery & Development Drug Delivery

Chemotherapy All Wrapped Up

| William Aryitey

Could exosome encapsulation be the secret to delivering higher potency in chemotherapy?

Manufacture Standards & Regulation

Problem Plants

Regulators come down hard on facilities that come up short.

Business & Regulation Standards & Regulation

Therapeutic Orphans

Neonates have been underserved, potentially missing out on life-giving scientific advances.

Discovery & Development Drug Delivery

A Future of Printing Powders?

3D printing is starting to sound attractive - but we really need to understand our powders.

Manufacture Packaging

Lost in Translation

Translating medicine packaging information for international markets is a major challenge.

Discovery & Development Drug Delivery

Don't Neglect Needles!

New drug delivery technologies have their place, but so too do traditional needle injections…

Discovery & Development Drug Delivery

All Eyes on Patches

Noven has developed around one-sixth of approved New Drug Applications for transdermal patches…

Discovery & Development Drug Delivery

Microneedles Point to the Future

With clinical trials under way, the commercialization of a microneedle patch is widely anticipated.

Discovery & Development Drug Delivery

All Aboard the Transdermal Express

Kirsty Gapp delves into trends and the benefits driving Transdermal and Microneedle Drug Delivery.

Discovery & Development Drug Delivery

Engineering Better Delivery

Samir Mitragotri talks us through his fascination with transdermal delivery.

Discovery & Development Drug Delivery

Insolubility Insight

Solubility is a key for drug delivery but pipelines are full of compounds with poor solubility.

Business & Regulation Formulation

Lean, Mean Stability Machine

The stability of drug formulations is essential. But what should be monitored – and how often?

Manufacture Advanced Medicine

Personalized Medicine × Nanotechnology

The combination of genomic profiling and high-tech targeted drug delivery is opening up a new front in the fight against cancer.

Business & Regulation Business Practice

Hail the Tattletale

Does incentivizing informants deter off-label drug marketing ? Should other countries follow suit?

Business & Regulation Business Practice

Deep Data Diver

Sitting Down With... Brian Overstreet, President at Advera Health Analytics, USA.

Discovery & Development Drug Delivery

Deep Breaths and Dry Powder

| Sponsored by Catalent

Drug delivery by inhalation promises convenience and speed in many applications from the emergency room to home-based self-administration. But to succeed, the interactions between formulation, device and metering mechanism must be perfectly balanced with human factors. These challenges are a source of fascination for those looking to deliver drugs less invasively.

Discovery & Development Analytical Science

Solving the challenges of Leachable pharmaceutical impurities using a full analytical portfolio

Extractables and leachable compounds are a complex and ever growing list of pharmaceutical impurities

Discovery & Development Analytical Science

Talking Extractables & Leachables with Smithers Rapra

Hear how new developments in analytical technology are providing additional insights into unknown contaminants

Discovery & Development Analytical Science

Talking Extractables & Leachables with Glaxo Smith Kline

Hear from industry expert Jason Creasey as he discusses the history of extractable and leachable testing

Other issues of 2016