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November 2016 Issue of The Medicine Maker

Welcome to the November issue. Upfront investigates a new vaccine for the common cold, brainiacs in a bar and a debate over off-label marketing. In our cover feature, find out how virtual reality and augmented reality are changing pharma manufacturing. NextGen asks whether traditional cleanroom infrastructure is about to become obsolete, and in Business, George A. Chressanthis argues that price controls may have negative implications for patient health. We also sit down with Steve Turley, Managing Director for the British and Irish Isles at UCB.

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Articles featured in this issue

Business & Regulation Technology and Equipment

The Times They Are a-Changin’

| Stephanie Vine

What impact will Brexit, a new US President, and a flood of new technologies have on the industry?

Business & Regulation Business Practice

Brainiacs in the Bar

| James Strachan

A podcast series lets listeners eavesdrop on a conversation between scientists in a bar

Business & Regulation Standards & Regulation

Side Effects? What Side Effects?

| James Strachan

Patients don’t always read drug risk information – even when they say they do

Manufacture Vaccines

The Cold War

| James Strachan

Is a vaccine for the common cold impossible? Scientists believe not

Discovery & Development Clinical Trials

Efficacy vs Effectiveness

| William Aryitey

Tightly controlled trials are poor predictors of real-world outcomes

Business & Regulation Standards & Regulation

The Great Off-Label Debate

| James Strachan

The FDA consults stakeholders over plans to loosen restrictions on off-label drug marketing

Manufacture Biosimilars

Generics Deliver Savings

| James Strachan

Our infographic shows how much can be saved with generic drugs

Manufacture Business Practice

Business-in-Brief

| James Strachan

Collusion, pollution, and a pricing victory for pharma in California… what’s new in business?

Manufacture Small Molecules

Serial Indecision

| Jean-Luc Lasne

With so many serialization solutions available, where do you start to make a decision?

Business & Regulation Business Practice

Open Your Mind

| Jackie Hunter

Open innovation done right can help overcome funding challenges and accelerate discovery

Manufacture Technology and Equipment

The Power of Plants

| Kathleen Hefferon

How plant-based vaccines could boost access to medicines in the developing world.

Manufacture Technology and Equipment

Harnessing Augmented Reality

| Angelo Stracquatanio

How Google Glass inspired hands-free access to information for process engineers.

Manufacture Technology and Equipment

Virtual Facility Design

| Ian Sellick

Virtual reality can let you walk around facilities before they have been built.

Manufacture Technology and Equipment

A New Angle for Marketing

| Nicolas Vertommen

Nicolas Vertommen tells the story behind HakoBio - a web-based platform for designing processes.

Manufacture Technology and Equipment

Entering Molecules

| Jonas Boström

Drug designers already use molecular visualization tools, but VR can take this to a new level.

Manufacture Technology and Equipment

Experiencing the KAVE

| James Strachan

Is virtual reality about to revolutionize pharmacy education and training?

Manufacture Technology and Equipment

The Machine Maker

Could VR be useful in the design of manufacturing equipment?

Manufacture Facilities

Podifying Cleanroom Processes

| Maik Jornitz

Will mobile, flexible cleanroom solutions make traditional cleanrooms obsolete?

Business & Regulation Business Practice

The Potential Pitfalls of Price Controls

| George A. Chressanthis

Evidence suggests that price controls could hamper innovation and negatively affect patient health outcomes.

Business & Regulation Business Practice

Pride and Passion

| Steve Turley

Sitting Down With Steve Turley, Managing Director for the British and Irish Isles, UCB.

Manufacture Analytical Science

Protein A: a Question of Affinity

| Sponsored by GE Healthcare

Is there a future for Protein A in affinity chromatography?

Discovery & Development Contract Development Services

A False Economy

| Sven Stegemann

There is a constant drive in the industry to reduce costs, but inexpensive supplies can prove a poor bargain.

Discovery & Development Business Practice

In Conversation with Dr Jean Luc Herbeaux of Evonik at CPhI Worldwide 2016

The Medicine Maker's Charlotte Barker speaks with Dr Jean Luc Herbeaux from Evonik

Discovery & Development Business Practice

In Conversation with Simon Edwards of Cambrex at CPhI Worldwide 2016

The Medicine Maker's Charlotte Barker speaks with Simon Edwards from Cambrex

Discovery & Development Business Practice

In Conversation with Gary Lord of Dow Corning Healthcare at CPhI Worldwide 2016

The Medicine Maker's Charlotte Barker speaks with Gary Lord from Dow Corning Healthcare

Discovery & Development Business Practice

In Conversation with Bernhard Paul of Johnson Matthey at CPhI Worldwide 2016

The Medicine Maker's Charlotte Barker speaks with Bernhard Paul from Johnson Matthey

Discovery & Development Business Practice

Use of microcalorimetry and its correlation with Size Exclusion Chromatography for rapid screening of the physical stability of large pharmaceutical proteins in solution

Learn how to use DSC to screen for physical stability of proteins in solution.

Discovery & Development Business Practice

Determining fluorescence Limit of Detection with Nanoparticle Tracking Analysis

NanoSight instruments can also operate in fluorescence mode where only fluorescently labeled particles are detected and measured. This application note works through an experiment to approximately establish a baseline in terms of the fluorescence limit of detection for a given fluorophore.

Other issues of 2016