Formulation

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Many drug candidates are as poorly soluble as “brick dust”, making oral delivery a significant challenge.

Polymorphic conversions are an ongoing problem in the pharmaceutical industry.

In this white paper, we report the use of the thermal stability data obtained from DSC to screen conditions for viral inactivation of an antibody1.

The rapid growth of the therapeutic antibody market has increased the interest in modeling of the antibody structure...

In this report, we illustrate the utility of calorimetry in making better laboratory decisions.

This study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.