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Formulation

Discovery & Development Drug Delivery

Using Raman Spectroscopy to Understand the Conformational Stability of Protein Therapeutics

| Sponsored by Malvern Panalytical

Use of a novel combination of dynamic light scattering and Raman spectroscopy to elucidate the conformational stability and structure of proteins in biopharmaceutical formulations

Discovery & Development Formulation

The Medicine Maker × Catalent Applied Drug Delivery Institute

| Sponsored by Catalent

There are many hurdles in drug development, but your chances of success increase significantly if you pay more attention to API optimization from the outset.

Manufacture Business Practice

Utilization of kinITC in AFFINImeter

| Sponsored by Malvern Panalytical

This application note describes how and when can kinetic information be retrieved from ITC power curves.

Discovery & Development Formulation

Benign by Design

Researchers redesign existing drugs to be more biodegradable and environmentally friendly.

Business & Regulation Business Practice

Studying low-affinity fragments of ligands by ITC

Dissecting a ligand into smaller fragments can provide a strategy for analyzing the role of key functional groups in a protein-ligand interaction.

Manufacture Business Practice

Nanoparticle Tracking Analysis: Principles and Methodology

It is well established that the use of nanotechnology in medicine and more specifically drug delivery is spreading rapidly.

Manufacture Business Practice

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Business & Regulation Formulation

A Cat and Mouse Game: The Evolving Landscape of Abuse-Deterrent Formulations

| Charlotte Barker

Abusers are finding ways to circumvent current abuse-deterrent measures, leaving companies in need of new strategies.

Discovery & Development Formulation

Addiction by Prescription

Prescription drug abuse has already reached epidemic proportions in the US – and other countries look set to follow the dangerous trend.

Manufacture Biosimilars

Taylor Dispersion Analysis for assessing the self-association and stability of Insulin

| Sponsored by Malvern Panalytical

Taylor Dispersion measurements are used to monitor self-association and oligomeric state in a variety of buffer conditions.

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