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Discovery & Development

Discovery & Development Formulation

The Placebo Effect

| David Banks

David Banks offers a warning on using inappropriate lyophilization placebos.

Discovery & Development Formulation

Can Slow and Steady Win the Cancer Race?

| James Strachan

Researchers say cancer should involve more frequent treatment at lower doses.

Discovery & Development Clinical Trials

Breaking the Habit

| James Strachan

With illegal drug use rising, can a cancer drug be repurposed to cure cocaine addiction?

Discovery & Development Business Practice

Using Taylor Dispersion Analysis to determine oligomeric state of insulin

In this article, we take an introductory look at how TDA works, the information it provides and its complementary application to other techniques within the drug development workflow. In addition, example case study data will showcase the performance of TDA relative to dynamic light scattering (DLS) for assessment of the impact of a range of parameters on the monomer-dimer-hexamer equilibrium of insulin.

Discovery & Development Biosimilars

Accelerating the development of generic pharmaceuticals

In this article, triple detection SEC and MDRS are considered within the context of characterizing complex drug formulations, with specific case studies and results illustrating their application.

Discovery & Development Business Practice

Resonant mass measurement as an analytical tool

Predicting and measuring protein aggregation is a critical challenge in the formulation of biopharmaceuticals. This article describes an analytical tool that hits the ‘sweet spot’ of protein aggregation measurement

Discovery & Development Business Practice

Gold therapy using dynamic light scattering

This article explains how dynamic light scattering (DLS) can be used to gather particle size distribution data for the successful use of nanosized colloidal gold in drug delivery applications.

Discovery & Development Small Molecules

Small But Not Forgotten

Large molecules may grab the bulk of industry headlines, but small-molecule drugs are still pulling their weight.

Discovery & Development Drug Delivery

The Soft Side of Drug Delivery

| Keith Tanner

Tablets and capsules are often the “go-to” choice in oral drug delivery, but what about innovations other areas?

Discovery & Development Drug Delivery

There Was Plenty of Room at the Bottom

| Merari Tumin Chevalier

What started as a vision of miniaturization is now beginning to have a profound influence on drug delivery.

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