Discovery & Development

Zap a tumor with radiation to trigger P-selectin expression, then release the drugloaded nanoparticles.

When an industry grows rapidly, innovative approaches are required to ensure sustainable growth. Here, we speak to leaders at Ireland’s National Institute for Bioprocess Research and Training – NIBRT – to find out how a focus on talent, training and technology is changing the face of the field.

After finally breaking into the US market, biosimilars have created a real buzz in the industry, but the best practice for demonstrating similarity can be daunting to say the least.

When it comes to film coating, there’s more than meets the eye. Is the drug or tablet core sensitive to acidity or moisture? What release profile is needed? And finally, how will the patient react to the finished product?

Few oral biologics have made it to market, and though the challenges are well known, the benefits are huge and the task is not impossible. New technologies can help.

Sitting Down With... Ibraheem “Ibs” Mahmood, President and Chief Executive Officer, DrugDev, founded in the UK and headquartered in King of Prussia, PA, USA.

Tumor cells and phages inspire a new drug delivery method targeting the placenta

Cell therapy successes are widely hailed as breakthroughs, but will adverse effects and patient deaths hold the field back?

Automated image analysis has been combined with Raman spectroscopy to achieve component-specific size and shape analysis of active ingredients, supporting and accelerating the commercialization of both innovator and generic pharmaceutical products.

Which equipment can measure how the particle size delivered by a dry powder inhaler (DPI) changes as a function of applied air flow rate, providing a deagglomeration profile which can be used to compare the performance of different formulations in a device and improve drug delivery.