Discovery & Development

Are you up-to-date with new analytical platforms that can give you the edge?

Tablets are the most common dosage form, but have you considered all of your options?

Experts come together to discuss the chemistry of solubility and the drug delivery solutions of the future for dealing with poorly soluble compounds.

Can hair follicles and nanotechnology help topical drugs overcome the skin barrier?

David Banks offers a warning on using inappropriate lyophilization placebos.

Researchers say cancer should involve more frequent treatment at lower doses.

With illegal drug use rising, can a cancer drug be repurposed to cure cocaine addiction?

In this article, we take an introductory look at how TDA works, the information it provides and its complementary application to other techniques within the drug development workflow. In addition, example case study data will showcase the performance of TDA relative to dynamic light scattering (DLS) for assessment of the impact of a range of parameters on the monomer-dimer-hexamer equilibrium of insulin.

In this article, triple detection SEC and MDRS are considered within the context of characterizing complex drug formulations, with specific case studies and results illustrating their application.

Predicting and measuring protein aggregation is a critical challenge in the formulation of biopharmaceuticals. This article describes an analytical tool that hits the ‘sweet spot’ of protein aggregation measurement