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April 2020 Issue of The Medicine Maker

We present The Medicine Maker 2020 Power List, which celebrates the great minds involved in the development of all therapeutics, from small molecules to biopharmaceuticals to advanced medicines. The list includes 60 inspirational professionals. Meanwhile in Upfront, researchers use silver nanoparticles to battle brain-eating amoeba, and a new drug to heal broken bones more quickly. In NextGen, we find out why plants could help accelerate the manufacture of a COVID-19 vaccine, and how lessons learned from decades of manufacturing mAbs are affecting processes for cell and gene therapies. Finally, we sit down with Stephen Tindal to discuss pharma forensics and mystery solving.

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Articles featured in this issue

Manufacture Advanced Medicine

Hot Topics at CAR-TCR 2020

| James Strachan

In what may have been one of the last advanced therapy meetings to go ahead for some time, delegates met in London in late February for CAR-TCR.

Manufacture Advanced Medicine

Peeking into the CGT Pipeline

| James Strachan

Intel shows a rise in cell and gene therapy development in the US, with China not far behind.

Manufacture Advanced Medicine

Advanced Medicine In Brief

| James Strachan

The world’s largest cell and gene CDMO, an exciting new TCR, and the global CAR T picture… We examine what’s going on in advanced medicine.

Discovery & Development Drug Discovery

The Battle Against the Brain-Eating Amoeba

| Maryam Mahdi

Novel compounds could be effective in treating brain-eating amoeba.

Discovery & Development Drug Discovery

Sticks and Stones

| Maryam Mahdi

Novosteo has developed a targeted drug combination to help accelerate the repair of bone fractures.

Business & Regulation Standards & Regulation

Pro Bono Advice

| Maryam Mahdi

The EMA is offering scientists free advice on the development of therapeutics to treat COVID-19.

Manufacture Vaccines

Coronavirus: A Synthetic Solution

| Eric van Hofe

What’s the fastest route to a COVID-19 vaccine?

Business & Regulation Standards & Regulation

Riding China’s Regulatory Rapids

| Matthias Bucerius

How can pharma companies keep up with the rapidly changing Chinese regulatory landscape?

Manufacture Formulation

The Rise of Lipid Nanoparticles

| Rahul Keswani, Benjamin King

With more complex molecules filling company pipelines, is it time for lipid nanoparticles to finally shine?

Manufacture Vaccines

Fast-Farming Pharma

How plants could speed up vaccine manufacture to tackle the COVID-19 pandemic.

Manufacture Advanced Medicine

Advanced Medicine: Replicating the mAb Success Story

| Stephanie Vine

How can manufacturing be improved for viral vectors?

Discovery & Development Drug Discovery

The Bumpy Road to a Cytomegalovirus Vaccine

| Andy Lane

The development of a CMV vaccine has been 50 years in the making.

Manufacture Technology and Equipment

The Glass Quality You Seek Does Exist

| Robert Schaut

Recent glass innovations can make a big difference to pharma manufacturers.

Manufacture Dosage Forms

The Forensic Troubleshooter

Sitting Down With... Stephen Tindal, Director, Science & Technology at Catalent Pharma Solutions, to discuss his career in troubleshooting.

Other issues of 2020