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March 2020 Issue of The Medicine Maker

From battling river blindness, to Ebola, to the threat of the coronavirus – March’s cover feature looks at how pharma is standing up to neglected tropical diseases and emerging pathogens. George Chressanthis explains why the coronavirus will have an economic impact on the pharma industry and what companies can do about it; and we catch up with new CEO, Stuart Young, about his change in role and the trends driving the business of clinical trials. In addition, Claudia Zylberberg makes the case for a regulatory framework for cell and gene ancillary materials; while the latest news, views and research, include a new polio vaccine, structure elucidation for natural products, and advice for budding entrepreneurs in the UK. We also sit down with “pharmaceutical nomad” and Chief Executive Officer at Bone Therapeutics, Miguel Forte.

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Articles featured in this issue

Discovery & Development Analytical Science

Natural Evolution of NMR Methodology?

| Stephanie Sutton

How do we determine the structure and stereochemistry of natural products?

Discovery & Development Drug Discovery

The Need to be Seen

| Maryam Mahdi

What is the current situation for rare diseases and orphan drug development?

Business & Regulation Profession

A Green Pioneer

| Maryam Mahdi

Celebrating a career dedicated to environmental protection with an international environmental award.

Manufacture Vaccines

Total Eradication

| Maryam Mahdi

A new polio vaccine could help eradicate the disease once and for all.

Business & Regulation Profession

A Word of Advice

| Maryam Mahdi

Looking to set up your own company but lacking a sense of business acumen? There may be help at hand.

Manufacture Vaccines

Solid Vaccines for Liquid Tumors

Researcher at the Wyss Institute have developed a biomaterial-based vaccine that reportedly eliminates acute myeloid leukemia.

Discovery & Development Drug Discovery

A Molecular Advantage

| Michael Schubert

How can advanced diagnostics be used to develop a new treatment for COVID-19?

Manufacture Advanced Medicine

Regulate with the Times

| Claudia Zylberberg

Claudia Zylberberg explains the importance of ancillary material quality for advancing cell and gene therapies.

Manufacture Advanced Medicine

Manufacturing by Design

| Frederic Revah

Let’s reduce gene therapy manufacturing costs by optimizing cell lines, improving transfectants, and optimizing downstream purification.

Business & Regulation Business Practice

Making Life a Little Bit Sweeter

| Simon Bush

Eliminating infectious diseases that lead to blindness in Africa – an eye-opening view from the frontlines featuring Sightsavers.

Manufacture Vaccines

Lending a Helping Hand

| Maria Elena Bottazzi, Bart Fryszczyn

How are industry and academia collaborating to tackle neglected diseases?

Manufacture Vaccines

What Lessons Have We Learned from Ebola?

| Stephanie Sutton

How can we ensure we are better prepared to develop new vaccines and treatments for future infectious disease outbreaks?

Business & Regulation Business Practice

Accepting Responsibility for Global Health

| Stephanie Sutton

We speak with Nik Kotecha, CEO of Morningside, to discuss why pharma companies have a responsibility to take the lead in helping others.

Business & Regulation Business Practice

Digitalization Now

| Stephanie Sutton

Digital technologies are here – but are they being used adequately?

Business & Regulation Business Practice

An Economic Infection

| George A. Chressanthis

The coronavirus is likely to have an economic impact on the pharma industry, but how bad will it be?

Manufacture Contract Development Services

Onward in Oncology: Lessons Learned with Carlo Toniatti

| Carlo Toniatti

Carlo Toniatti takes us on a journey from the clinic, to academia, to industry, and shares his lessons learned along the way.

Business & Regulation Business Practice

Changing the Clinical Trials Game

| Stephanie Sutton

We catch up with a new CEO about his goals for a clinical trials business.

Manufacture Advanced Medicine

The Pharmaceutical Nomad

| James Strachan

Sitting Down With... Miguel Forte, Chief Executive Officer at Bone Therapeutics, Belgium, to discuss advanced medicine.

Other issues of 2020