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September 2020 Issue of The Medicine Maker

From the fringe of the fringe to the brink of a revolution in medicine – we get the cell and gene therapy story from the society that was there at the very beginning: ISCT – in this month’s cover feature. Best Practice looks at the importance of the patient voice in drug development, and why single-use systems have come to be so well regarded. In NextGen, we find out about the problem with patents when it comes to artificial intelligence. We also sit down with Kelly Chibale to discover his passion for Africa’s pharma industry.

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Articles featured in this issue

Manufacture Quality & Compliance

When Fast Science Spells Bad Science

| Stephanie Sutton

Drug development needs to move more rapidly, but not at the expense of safety.

Discovery & Development Clinical Trials

A Matter of Trust

| Maryam Mahdi

Can we trust the integrity of clinical trials?

Manufacture Advanced Medicine

CRISPRing Up Brown Fat

| James Strachan

Joslin Diabetes Center researchers take the first steps towards an autologous cell therapy for obesity.

Manufacture Bioprocessing - Single Use Systems

The Power List 2021: Nominate Now

| Stephanie Sutton

Nominations are now open for The Medicine Maker 2021 Power List.

Manufacture Vaccines

Save Our Shots!

| Stephanie Sutton

GlaxoSmithKline has launched a vaccine awareness campaign in the USA as immunization rates drop amidst the pandemic.

Business & Regulation Business Practice

End of an Era

| Maryam Mahdi

The UK’s medicines regulator releases new guidance for Brexit.

Discovery & Development COVID-19

The COVID-19 Curator

| Stephanie Sutton

Your roundup of the key scientific studies and industry announcements emerging from the pandemic.

Manufacture Advanced Medicine

Let’s Focus on Filtration

| Morven McAlister, Aernout Martens

Gene therapy manufacturers will need to focus on upstream filtration to minimize the risk of viral infection.

Discovery & Development Analytical Science

Quality Control: The Power of Precision

| Mark Lies

One analytical technique that is seeing increasing popularity, in part due to its precision and reproducibility, is capillary electrophoresis.

Business & Regulation Business Practice

The Pandemic Diaries

| Zahid Tharia, David Underwood, Kenneth Lee, Mike Jagielski, Ger Brophy

We ask medicine makers around the world to tell us how their professional and personal lives have changed over the course of the COVID-19 crisis.

Manufacture Advanced Medicine

“Curing Cancer? That’s Cute”

| James Strachan

Cell and gene therapies are now considered mainstream therapeutic modalities – with revolutionary potential. But that hasn’t always been the case…

Manufacture Advanced Medicine

How to Deliver a Virtual Conference in Under Two Months

| Queenie Jang

Queenie Jang reveals how the ISCT created an interactive virtual conference in under two months.

Discovery & Development Drug Delivery

The Patient Voice

| Sven Stegemann

It is essential that drug development incorporates the patient view.

Manufacture Bioprocessing - Single Use Systems

Charting the Rise of Single Use

| Stephanie Sutton

Single-use systems have come a long way. We look at experience with the technology so far.

Manufacture Advanced Medicine

Candidate Commercialization: A Helping Hand

| Kenneth Lee

How to drive antibody drug development and manufacture forward safely and quickly.

Discovery & Development Drug Discovery

Does AI Dream of Electric Patents?

| Amy Nick

When it comes to using AI in drug development, companies need to consider how they create and protect their intellectual property.

Business & Regulation Business Practice

If You Build It, They Will Come

| Maryam Mahdi

Sitting Down With... Kelly Chibale, Director, H3D, University of Cape Town, South Africa.

Manufacture Packaging

Good Things Come in Small Packages

| Sponsored by Schott

SCHOTT introduces an online shop with low minimum order quantities to overcome the challenges associated with conventional purchase order procedures.

Other issues of 2020