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January 2020 Issue of The Medicine Maker

Welcome to the January issue! There will be another recession – as certain as night follows day – but, our cover feature asks, how bad will it be? And is the pharma industry prepared? In Upfront, we explore how digital tech is fighting fake medicine, and how computer simulations are improving ADC linkers. Araksya Topchyan highlights the importance of drug-nutrient interactions in In My View; while NextGen asks: what happens if you try to apply open source to pharmaceutical R&D? Last but not least, we Sit Down With Jane Osbourn, Chair at Mogrify and the UK BioIndustry Association.

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Articles featured in this issue

Manufacture Biosimilars

New Decade, New Hope

| Stephanie Sutton

Cures for all presents a real focus for the next decade – but companies must be rewarded for their work.

Discovery & Development Drug Discovery

Fungal (Library) Growth

| Maryam Mahdi

Jeroen den Hertog from the Hubrecht Institute is exploring the bioactive properties of fungal strains.

Manufacture Packaging

The Pack of the Future

| Maryam Mahdi

How can pharmaceutical packaging be adapted to meet patient and supply chain requirements?

Manufacture Packaging

The Industry Strikes Back

| Maryam Mahdi

How are digital technologies addressing supply chain challenges?

Discovery & Development Drug Discovery

Image of the Month

Bacteria shredding liquid metals to fight drug-resistant superbugs.

Manufacture Drug Delivery

Synthetic Silos

| Maryam Mahdi

A synthetic system which mimics the compartmentalized nature of cells could help in the delivery of drugs.

Discovery & Development Drug Discovery

LEGO Linkers for ADCs

| Maryam Mahdi

A new computational tool could help improve the stability and predictability of ADCs.

Business & Regulation Business Practice

For the Many

| Charles Gore

The pharmaceutical industry must be encouraged to look beyond patients in advanced economies.

Manufacture Small Molecules

The Excipient of the Future

| Dieter Lubda

How will the adoption of novel approaches to the development of excipients help overcome the challenges of poorly soluble APIs?

Business & Regulation Business Practice

The Next Great Recession

| George Chressanthis

Is the pharma industry ready for another recession?

Discovery & Development Drug Discovery

Meet “Molecule” – the Pharma Development Disruptor

| Paul Kohlhaas

Can open source by applied to pharma R&D? This is the aim of Molecule.

Discovery & Development Drug Delivery

Breathing Easy

| Stephanie Sutton

How will inhaled therapies evolve? Lei Mao at Recipharm gives his take on the future of these therapies.

Business & Regulation Profession

A Framework for Translation

| Andrew Davies, Nigel Blackburn

Keeping the patient in mind is crucial for clinical research.

Business & Regulation Business Practice

Sitting Down With... Jane Osbourn

| James Strachan

Jane Osbourn talks about the potential of the UK's cell and gene therapy space.

Other issues of 2020