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September 2019 Issue of The Medicine Maker

Welcome to the September issue where our cover feature explores the microbes living in and on our bodies – and what they mean for drug discovery. Upfront asks: can gender bias skew preclinical results? And could a mosaic-based vaccine offer at-risk people more choice when it comes to HIV prevention? Sue Springett highlights the importance of health and safety in the lab, in In My View; and in Business, we speak with Ron Kander and Parviz Shamlou about Jefferson’s Institute for Bioprocessing, and Maeve Magner explains how digital solutions can improve the supply chains of emerging economies. Finally, we Sit Down With Joan Mannick, Co-Founder and Chief Medical Officer at resTORbio, Massachusetts, USA.

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Articles featured in this issue

Business & Regulation Trends & Forecasts

Redefining Pharma

| James Strachan

Should pharma companies transition from developing, manufacturing and pricing “drugs” to promoting “health”?

Discovery & Development Clinical Trials

Choice Matters

| Maryam Mahdi

A new vaccine could help give people at risk of HIV more options.

Discovery & Development Analytical Science

Quality Analysis for Life

| Paula Hong, Antonio Ramos

"Let's adopt a lifecycle management approach to method development to ensure continued excellence."

Discovery & Development Clinical Trials

Giving Data the Gift of Meaning

| Gen Li, Jonathan Peachey

Clinical trials need an overhaul – and AI is the solution.

Manufacture Advanced Medicine

Choose Your Playing Field

| Grace Linton, Charles Heffernan

Before you start building a new ATMP facility, there is one essential element that you need to get right: site selection.

Discovery & Development Clinical Trials

Of Men and Mice

| James Strachan

Male animal bias in preclinical research isn’t scientifically justified and may be skewing our understanding of the brain.

Discovery & Development Formulation

Get your Coat!

| Maryam Mahdi

Researchers at the University of Bath have developed a technique which could prevent drugs from spoiling.

Business & Regulation Business Practice

On the Side of Caution

| Sue Springett

Sue Springett, Commercial Manager at Teknomek, explains the importance of health and safety in a solid coroporate social responsibility strategy.

Manufacture Dosage Forms

The Power of Productivity

| Kelly Boyer

Tablet coating is not just about aesthetics; a good coat will improve stability, aid patient adherence, and enhance manufacturing productivity.

Manufacture Bioprocessing - Upstream & Downstream

The Holistic Approach to Upstream Viral Safety (MilliporeSigma)

| Craig Jackson, Michael Cunningham

There could be significant benefits to implementing additional measures in upstream bioprocesses to prevent viral contamination.

Manufacture Contract Manufacturing Services

When Standardization Meets Customization

| Jeremy Rautenbach

Combine standardized, single-use platform technologies that can be customized to your particular process requirements, for crucial efficiency gains.

Manufacture Facilities

Innovation in Biopharma Education

| James Strachan

The Jefferson Institute for Bioprocessing is up and running after just two years. How did they do it? And what courses are on offer?

Business & Regulation Supply Chain

A Digital Transformation in Supply

| Maryam Mahdi

Maeve Magner explains how digital solutions can improve the supply chains of emerging economies.

Discovery & Development Drug Discovery

Putting the Brakes on Aging

| Maryam Mahdi

Sitting Down With… Joan Mannick, Co-Founder and Chief Medical Officer at resTORbio, Massachusetts, USA.

Other issues of 2019