Ingredients

Functionalized glass is shown to trigger nucleation of specific crystal forms

Industry is beginning to appreciate how formulation microstructure makes a fundamental contribution to dermal drug delivery – and this new understanding emphasizes the key role of excipients.

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Polymorphic conversions are an ongoing problem in the pharmaceutical industry.

Protein interactions define a large fraction of the validated targets for drug development including cancer, diabetes, infection and autoimmune diseases.

Use of a novel combination of dynamic light scattering and Raman spectroscopy to elucidate the conformational stability and structure of proteins in biopharmaceutical formulations

There are many hurdles in drug development, but your chances of success increase significantly if you pay more attention to API optimization from the outset.

Two antibody samples were characterized using column calibration and multi-detection SEC, and the results compared...