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Discovery & Development Ingredients, Formulation

The Grand Winner

The wait is over. Voting for The Medicine Maker Innovation Awards has ended and we are delighted to announce our grand winner: Lubrizol Life Science Health’s Apisolex Polymer.

This innovation is an injectable-grade excipient that can help enhance the solubility of BCS class II and IV APIs by around 50,000 fold. It is designed to work with simple formulation techniques, with a view to streamlining manufacturing and minimizing API loss with a high encapsulation rate. According to Lubrizol, the solubilizing excipient and API can be mixed in an aqueous-based solution followed by sterile filtration and lyophilization. The approach forms micellar structures that encapsulate the API during lyophilization, and the resulting formulation is stable and can be readily resuspended in common diluents for administration. In saline, the lyophilized drug product reconstitutes in less than 30 seconds.

You can look forward to finding out more about this technology in a future issue of The Medicine Maker.

Joey Glassco, Global Market Manager at Lubrizol Life Science, Health, said, "We are honored for Apisolex solubilizing excipient to be recognized by readers of The Medicine Maker for this prestigious innovation award. My hope is that winning this award will allow drug formulators struggling with water-insoluble APIs to learn about the polymer’s benefits so that more life-changing medications can make it to market." 

The Innovation Awards annually showcase new drug development and manufacturing technology that has hit the market. In 2022, we received a record number of nominations for new technologies. The top 12 was published in December 2022, but to decide our grand winner, we asked readers and visitors to The Medicine Maker website to vote for their favorite technology.

Honorable mentions go out to Terumo Blood and Cell Technologies Quantum Flex Cell Expansion System and Thermo Fisher Scientific’s Direct Mass Technology Mode.

Nominations for the 2023 Innovation Awards will open soon. Keep your eyes peeled:

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About the Author
Stephanie Vine

Making great scientific magazines isn’t just about delivering knowledge and high quality content; it’s also about packaging these in the right words to ensure that someone is truly inspired by a topic. My passion is ensuring that our authors’ expertise is presented as a seamless and enjoyable reading experience, whether in print, in digital or on social media. I’ve spent fourteen years writing and editing features for scientific and manufacturing publications, and in making this content engaging and accessible without sacrificing its scientific integrity. There is nothing better than a magazine with great content that feels great to read.

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