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November 2023 Issue of The Medicine Maker

We celebrate new technologies for drug development and manufacturing with our 2023 Innovation Awards. Don’t forget to vote for the grand winner! Also in this issue; vaccines for healthcare-associated infections, genetically engineered yeast for making medicines, modernizing quality control operations, improving AAV production, applying machine learning to oligonucleotide manufacturing, and more. The BPSA gives us the lowdown on X-ray sterilization and ten23 health’s Hanns-Christian Mahler talks sustainability.

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Articles featured in this issue

Discovery & Development Drug Delivery

One Vaccine to Rule Them All

| Jamie Irvine | 2 min read

A superbug vaccine could protect patients against multiple healthcare-associated infections at once

Manufacture Quality & Compliance

Shouldn’t We Modernize Quality Control Operations?

| Jason Boyd | 4 min read

Three steps to drive meaningful change in quality control.

Discovery & Development Drug Discovery

The FLEET of Hope

| Robert H Cichewicz | 3 min read

Fungal infections and antifungal resistance are a significant problem; here’s one approach to consider

Manufacture Facilities

Uniting a Cell and Gene Kingdom

| Jamie Irvine | 2 min read

Exploring the ins and outs of a recent UK-based collaboration between two prominent advanced medicine players

Manufacture Advanced Medicine

Improving AAV Production

| Jamie Irvine | 3 min read

How a three-way collaboration aims to use digital twins to refine the efficiency of adeno-associated virus manufacture

Manufacture Facilities

Cell Culture Media Is Big Business

| 4 min read

Merck’s Darren Verlenden discusses the strategy and ethics behind the expansion plan in Lenexa, Kansas

Manufacture Advanced Medicine

Putting the “Go” in Oligonucleotide Manufacturing

| Ben Pellegrini | 3 min read

Intellegens CEO Ben Pellegrini explains how machine learning is set to change the oligonucleotide manufacturing landscape

Business & Regulation Business Practice

Active Manufacturing Responsibility and the Other AMR

| Marijn Verhoef, Martijn van Gerven | 5 min read

Experts from the Access to Medicine Foundation discuss how to reduce the risk of antimicrobial resistance (AMR) in antibiotic manufacturing.

Manufacture Bioprocessing - Single Use Systems

Keeping Up To Date With X-Rays

| Jamie Irvine | 7 min read

We speak with the BPSA to find out why X-ray sterilization is being considered as an alternative to gamma irradiation

Discovery & Development Drug Delivery

In Search of Lost Memory

| Jamie Irvine | 12 min read

An insight into the complexities of Alzheimer’s disease and the ongoing pursuit for breakthrough therapies

Manufacture Facilities

Taking Sustainability to Heart: An Interview With ten23 Health

| Stephanie Vine | 11 min read

We sit down with Hanns-Christian Mahler, CEO of ten23 health.

Other issues of 2023