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June 2023 Issue of The Medicine Maker

Find out how CRISPR genome editing technologies are shaping the future of drug development; we ask experts about the hype versus reality. Also in this issue, patient centricity at Boehringer Ingelheim, real-world data, and why the pharma industry shouldn’t ignore the need for dengue treatments. Academics explain how they have converted plastic waste into pharmaceutical APIs, members of our Power List explore the challenges facing cell and gene therapy, and we invite you to learn more about the importance of crystallization for API manufacturing.

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Articles featured in this issue

Discovery & Development Formulation

Superbugs Versus Supercomputers

| Jamie Irvine | 2 min read

Developments in antivirulence drug treatments could solve the threat of antimicrobial resistance

Discovery & Development Drug Discovery

Nut a Problem

| Jamie Irvine | 2 min read

Immunotherapy Viaskin Peanut shows promising results in desensitizing peanut-allergic toddlers.

Discovery & Development Clinical Trials

Putting Real-World Data to Work

| Karen Ooms | 4 min read

How do we further integrate real-world data into clinical research and approval processes?

Business & Regulation Trends & Forecasts

Patient-Centric Perspectives

| Keri Yale | 5 min read

Patient-centricity needs to be more than a buzzword. Here’s how Boehringer Ingelheim is weaving it into its culture.

Discovery & Development Drug Discovery

The Dangers of Dengue

| Neelika Malavige | 4 min read

We need more investment for research into dengue treatments that can curb the overwhelming pressure placed on healthcare systems.

Discovery & Development Drug Delivery

Power List Perspectives: Challenges Facing Cell and Gene Therapy

| Jamie Irvine

Leading pharma industry experts discuss the most pertinent challenges facing cell and gene therapy

Manufacture Biosimilars

The Imperfect Art of Biosimilars

| Dave Li, Anna Baran | 5 min read

Need a refresher on biosimilars? Here, we offer some key points to keep in mind when it comes to structure, function, and interchangeability.

Discovery & Development Ingredients

From Plastic Pollution to Pharma Compounds

| Stephanie Vine | 3 min read

How fungi help turn ocean trash into pharmaceutical platform molecules.

Manufacture Bioprocessing - Upstream & Downstream

mAbs: Not so Sweet

| Neha Mishra, Jesus Zurdo | 9 min read

How fucosylation-deficient CHO cell hosts can help enhance the potency of monoclonal antibody-based biotherapeutics

Manufacture Small Molecules

The Dark Crystal

| Andrew Blythe-Dickens | 7 min read

Though crystallization is considered a “black art” in some circles, it’s still a crucial part of the API manufacturing process

Other issues of 2023