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July 2023 Issue of The Medicine Maker

Antibody drug conjugates have been hailed as “magic bullets” for years. Are they finally about to live up to the hype? Experts in our cover feature discuss. Also in this issue; we speak with Lubrizol, which won an Innovation Award for itssolubility-enhancing excipient Apisolex; learn about oligonucleotides from CatSci’s Nigel Richardson; and find out why new approaches are needed for antimicrobial resistance. We also sit down with Tirtha Chakraborty from Vor Bio and take a look at the top prospects in the cell and gene sector.

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Articles featured in this issue

Business & Regulation Digital Technologies

The ADHD Video Game – for Adults

| Stephanie Vine | 2 min read

Akili Interactive releases a new version of its ADHD treatment game for adults.

Discovery & Development Drug Discovery

Honey, I Shrunk the Molecules

| Jamie Irvine | 2 min read

Researchers demonstrate that microRNA-132 can significantly affect different brain cells, with potential implications for Alzheimer’s disease.

Discovery & Development Drug Delivery

Remote Controlled Chemo

| Jamie Irvine | 3 min read

Meet MAPSULES: metal iron-based nanocapsules that deliver targeted chemotherapy to solid tumors

Discovery & Development Drug Discovery

To Be Precise

| Neil Ward | 3 min read

Better data brings new advances in our knowledge of genetics. PacBio VP Neil Ward explains how pharmacogenomics will accelerate precision medicine.

Manufacture Vaccines

Ode to the Microbe

| Kyle Probst | 4 min read

Understanding the role of microbial fermentation in the production of mRNA vaccines.

Discovery & Development Drug Delivery

Revenge of the ADCs

| Stephanie Vine | 15 min read

Are antibody drug conjugates (ADCs) the breakthrough in cancer treatment? Experts share insights on recent advancements

Discovery & Development Drug Discovery

A Call to Arms for Antimicrobial Resistance

| Peter Jackson | 13 min read

Investment into new antimicrobial therapies has been lacking for decades – and now we’re now paying the price.

Manufacture Packaging

Blisters of Mercy

| 7 min read

Child exposure to pharmaceutical substances appears to be decreasing, but what more can packaging companies do to push the trend?

Manufacture Technology and Equipment

Getting Results Through Novel Solubility-Enhancing Excipients

| 7 min read

Innovation begins as an idea, but partnerships give it life. We speak to Joey Glassco, LLS Health, about Apisolex, our 2022 Innovation Awards winner.

Manufacture Advanced Medicine

The ‘Tides are Turning

| Rob Coker | 5 min read

Oligonucleotides are a complex but promising new modality in therapeutics. Director of New Modalities at CatSci Nigel Richardson explains why.

Business & Regulation Business Practice

A Roadmap to Greener Pharma Logistics

| Julius Graf von Pfeil, Kees Schmidt | 10 min read

How to make the art of pharmaceutical logistics more sustainable.

Discovery & Development Drug Discovery

Afraid of Banality, Driven by Beauty

| 5 min read

Sitting Down With … Tirtha Chakraborty, Chief Scientific Officer at Vor Bio

Other issues of 2023