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Tosoh Bioscience is a leading manufacturer in the field of liquid chromatography with a special focus on bioseparation. The portfolio of over 500 specialty products encompasses instruments for size exclusion/gel permeation chromatography (SEC/GPC) and a comprehensive line of media and (U)HPLC columns for all common modes of liquid chromatography. Latest product innovations include UHPLC column lines for SEC analysis of protein fragmentation/aggregation and high capacity ion exchange, multimodal and Protein A media for the purification of therapeutic proteins and other biologics.

Tosoh Bioscience GmbH
Im Leuschnerpark 4
64347 Griesheim (Darmstadt), Germany
Phone: +49 6155-7043700
Fax: +49 6155-8357900
Email: [email protected]

Company website

Content by Tosoh:

Manufacture Trends & Forecasts

ECOnti: Sustainable Steps Towards Continuous Processes

| Sponsored by Tosoh | 7 min read

How Tosoh Biosciences is contributing to a fascinating project on a mission to develop a continuous production process using Escherichia Coli

Manufacture Bioprocessing - Upstream & Downstream

High Intensity Purification

| Sponsored by Tosoh

How can multi-column chromatography support companies as they set their sights on intensified bioprocesses?

Manufacture Bioprocessing - Upstream & Downstream

Speeding up the Development of Purification Methods

| Sponsored by Tosoh

Since the beginning of the pandemic, the public has realized how essential the biotechnology industry is in securing our civilization's future.

Discovery & Development Drug Discovery

Understanding the Oligonucleotide Landscape

| Sponsored by Tosoh

Oligonucleotide-based therapeutics present manufacturers with specific processing and characterization challenges.

Discovery & Development Analytical Science

A New Dawn in Biological Therapies?

| Sponsored by Tosoh

Explore TOSOH’s expertise across all stages of therapeutic antibody development.

Manufacture Bioprocessing - Upstream & Downstream

Easing Ion-Exchange Chromatography

| Romain Dabre

Why salt-tolerant resins make for “happier” biomolecules with better binding.

Manufacture Analytical Science

The New Antibody Formats on the Block

| Patrick Endres

Innovation is being boosted in manufacturing and purification techniques.

Manufacture Bioprocessing - Upstream & Downstream

The Smart Choice

01/01/1970 | Jonas Wege

Using the right chromatography resin can make all the difference to antibody fragment manufacture

Development of a universal preparative AEX method to purify oligonucleotides

| Contributed by Tosoh

Oligonucleotide-based therapeutics have been investigated over the last decades and their promise as a new drug modality is now being realized.

Effective Removal of mAb Aggregate Using Ca++Pure-HA® Media with Potassium Salts

| Contributed by Tosoh

Discover the better performance of Ca++Pure-HA

How to Improve the Capturing of Antibody Fragments

| Contributed by Tosoh

We developed a capturing method for antibody fragments that allows reducing the costs of the step by almost 80%.

Simple and Effective Method for Purification of DMT-ON Oligonucleotides using HIC Resins

| Contributed by Tosoh

The use of synthetic oligonucleotide therapeutics continues to grow because of their effectiveness in the treatment of devastating diseases.

Characterization of Recombinant Protein Biotherapeutics by UHPLC-SEC-MALS

| Contributed by Tosoh

Biotherapeutics are generally larger molecules such as peptides, proteins and monoclonal antibodies

HPLC Column for quick Evaluation of ADCC Activity

| Contributed by Tosoh

In many stages of mAb development, cell culture samples must be screened for IgG titer.

Reduce Downstream Processing Costs for mAbs by Switching to Tosoh’s 2-Step Platform

| Contributed by Tosoh

Downstream processing is responsible for up to 80 percent of the entire production costs of biotherapeutics.

Solutions for the Separation of Oligonucleotides

| Contributed by Tosoh

The first antisense drugs were approved, and clinical trials using siRNA show promising developments.

Bioprocessing application notebook - The best purification methods for your biomolecules

| Contributed by Tosoh

Discover over twenty application notes on biopharmaceutical purification.

TOYOPEARL PPG-600M: the HIC resin for the purification of ADCs

| Contributed by Tosoh

Antibody-drug conjugates (ADCs) are promising anticancer biopharmaceuticals with one of the highest annual growth rates.

TOYOPEARL Sulfate-650F - an ion exchanger that binds proteins under atypical conditions

| Contributed by Tosoh

TSKgel mAb SEC Columns – Setting new Benchmarks for Antibody Analysis

| Contributed by Tosoh

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