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November 2015 Issue of The Medicine Maker

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Articles featured in this issue

Business & Regulation Business Practice

M&A Merry-Go-Round

| Charlotte Barker

Round and round she goes, where she stops nobody knows. How will the current merger and acquisition fever affect the industry?

Manufacture Drug Delivery

Plant Protein Potential

| Stephanie Vine

Can lettuce really help biopharmaceuticals turn over a new leaf? Researchers certainly think so.

Manufacture Drug Delivery

Drugs in Disguise

How to dress drugs to help them survive in the bloodstream.

Business & Regulation Standards & Regulation

Breaking Bad Language

Can certain buzzwords really sway public perceptions of a new drug?

Discovery & Development Drug Delivery

A Soluble Solution for Drug Delivery

| Stephanie Vine

Could an ionic liquid–drug system help solve drug insolubility?

Discovery & Development

Herpes vs Cancer

| Stephanie Vine

A newly approved oncolytic immunotherapy takes on cancer using a live modified herpes virus

Manufacture Business Practice

Nobel Prize for Noble Causes

| Stephanie Vine

The 2015 Nobel Prize in Physiology or Medicine praises advances in parasitic tropical diseases.

Manufacture Bioprocessing - Upstream & Downstream

Exploring the Product–Process Relationship

Should product innovation or process innovation come first in biopharmaceuticals?

Business & Regulation Business Practice

What’s in a Name?

Changing your company name takes more than putting a new sign on the door.

Business & Regulation

Treating Before Infection?

What if we could treat bacterial infection earlier and without adding to drug resistance?

Discovery & Development Drug Delivery

Sparking Innovation in Drug Delivery

| Richard N. Dalby

In an industry as diverse as pharmaceuticals, there is much that different disciplines can learn from each another.

Business & Regulation Contract Development Services

When Outsourcing Goes Astray

“The best-laid schemes o’mice an’ men” often go awry – and that can apply to your outsourcing plans.

Business & Regulation Business Practice

The Journey from Chemist to Entrepreneur

| Elizabeth Thomas

Starting a bioanalytical research company after years working for Big Pharma has been daunting…

Business & Regulation Business Practice

The Realities of a Digital World

Advanced digital technologies are sweeping through the world and changing the way we live our lives and do business.

Business & Regulation Standards & Regulation

The Receptive Regulator

We sit down with Siu Ping Lam, Director of Licensing Division at the UK's Medicines and MHRA.

Manufacture Bioprocessing - Upstream & Downstream

Breaking the Bioprocessing Bottleneck

| Sponsored by GE Healthcare

The challenges of battling bottlenecks in downstream processing. Sometimes a fresh pair of eyes can find new and surprising solutions.

Manufacture Standards & Regulation

A New Era of E&L Analysis

| Sponsored by Thermo Fisher Scientific

New technologies for extractables and leachables testing of small molecules and biopharmaceuticals.

Discovery & Development Business Practice

The application of MicroCal VP Capillary DSC at a contract development organization

A case study involving the formulation development of a monoclonal antibody is presented to detail the utility and potential limitations of DSC in support of preformulation for a variety of protein products.

Discovery & Development Business Practice

Evaluating the rheological properties of hyaluronic acid hydrogels for dermal filler applications

This study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.

Discovery & Development Business Practice

Application of microcalorimetry in drug discovery at Exelixis

In this report, we illustrate the utility of calorimetry in making better laboratory decisions.

Discovery & Development Business Practice

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies

The rapid growth of the therapeutic antibody market has increased the interest in modeling of the antibody structure...

Manufacture Business Practice

Targeting protein/protein interactions in drug design

Protein interactions define a large fraction of the validated targets for drug development including cancer, diabetes, infection and autoimmune diseases.

Other issues of 2015