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July 2015 Issue of The Medicine Maker

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Articles featured in this issue

Business & Regulation Business Practice

The Epidemic That Cannot Be Ignored

| Charlotte Barker

The US Centers for Disease Control and Prevention has officially declared an “epidemic of prescription drug abuse”.

Manufacture Small Molecules

Highly Potent; Highly Targeted

| Stephanie Vine

A new mathematical model aims to improve drugs for cancer, viruses and bacteria.

Manufacture Vaccines

Green Light for Malaria Vaccine

| Stephanie Vine

After 28 years of R&D at GSK, the world has its first malaria vaccine.

Manufacture Biosimilars

Riddle Me This, Biosimilar

| Stephanie Vine

The first US biosimilar - Zarxio from Sandoz - has been cleared for market. But the judges say it wasn't an easy decision.

Manufacture Small Molecules

(Anti)Bacterial Factory

| Stephanie Vine

Engineered E. coli colonies could be trump cards in the war against drug resistance.


Biomimetic Protection of Biomolecules

| Stephanie Vine

Porous shells - inspired by sea urchins - help defend biomacromolecules from the outside world.

Manufacture Small Molecules

Recall Roundup

| Stephanie Vine

Several companies are faced with recall woes thanks to insects, dodgy closures and broken tablets.

Manufacture Small Molecules

A Blast From Potions Past

Are ancient texts hiding the answer to antibiotic resistance?

Manufacture Analytical Science

Multimodal Spectroscopy: Production Workhorse

Manufacturing is getting smarter; only a cross-discipline approach will ensure the success of tomorrow’s processes.

Manufacture Business Practice

Fake Medicine, Genuine Risk

How can we fight the global pandemic of falsified and substandard medicines?

Discovery & Development Formulation

Addiction by Prescription

Prescription drug abuse has already reached epidemic proportions in the US – and other countries look set to follow the dangerous trend.

Business & Regulation Formulation

A Cat and Mouse Game: The Evolving Landscape of Abuse-Deterrent Formulations

| Charlotte Barker

Abusers are finding ways to circumvent current abuse-deterrent measures, leaving companies in need of new strategies.

Manufacture Small Molecules

Is Biopharma Ready to Say Goodbye to Batches?

| Ronald A. Rader, Eric S. Langer

The biopharma industry has a long way to go before it’s ready to embrace superior manufacturing models. Why?

Manufacture Small Molecules

Decision Support

Farid and her team have developed a range of software tools to help biopharma companies make decisions on the best manufacturing processes.

Discovery & Development Business Practice

Fighting Fear – the Entrepreneur’s Enemy

The true path to success as an entrepreneur is the ability to spot high impact problems – and to be fearless in the pursuit of great solutions.

Manufacture Small Molecules

Precision Biomanufacturing

| Jonathan Robinson

Personalized medicine looks set to transform the biopharma landscape, and will demand significant changes in production methods.

Business & Regulation Biosimilars

The Business of Biosimilars

| Charlotte Barker

Sitting Down With… Carsten Brockmeyer, CEO, Formycon, Germany.

Business & Regulation

The Medicine Maker Innovation Awards 2015

| Charlotte Barker

The December issue will feature our inaugural Innovation Awards, recognising the most exciting new technologies of 2015.

Discovery & Development Standards & Regulation

Holistic Bioanalytics in the Clinic

| Sponsored by Agilent

Lawrence (Larry) Lesko is a bioanalytical veteran with many years of academic and FDA experience under his belt.

Manufacture Business Practice

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Manufacture Business Practice

Nanoparticle Tracking Analysis: Principles and Methodology

It is well established that the use of nanotechnology in medicine and more specifically drug delivery is spreading rapidly.

Business & Regulation Business Practice

Studying low-affinity fragments of ligands by ITC

Dissecting a ligand into smaller fragments can provide a strategy for analyzing the role of key functional groups in a protein-ligand interaction.

Other issues of 2015