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August 2021 Issue of The Medicine Maker

We take a deep dive into the cell therapy sector in our cover feature and ask what progress is being made in the fight against solid tumors. Meanwhile in NextGen, researchers from Carnegie Mellon University explain how AI can be used to source new pharmaceutical compounds derived from natural sources. Pierre Bourdage, Global Head of Biopharmaceuticals at Sandoz, also gives his take on the future of biosimilars, in Business. We also sit down with Andrew Moore, who tells us how he has used his military experience to inform his approach to leadership in the pharmaceutical industry.

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Articles featured in this issue

Discovery & Development Drug Discovery

Marrying Up Proteins using Molecular Glues

| Angus Stewart

A husband-and-wife-led team used mass spec to identify new drugs that “glue” proteins together. We spoke to Aneika Leney about the project.

Discovery & Development Clinical Trials

Hope in the Fight Against Malaria

| Angus Stewart

Can a new malaria vaccine hold the key to reliable, durable protection?

Discovery & Development Drug Discovery

Nano-Origami Versus Infectious Agents

| Angus Stewart

It was by serendipity that Hendrik Dietz learned how to make a virus trap. Now, his team may be sitting on a new way to combat disease.

Business & Regulation Standards & Regulation

High Fines for High Prices

| Stephanie Vine

Advanz Pharma is fined for substantially hiking the price of a generic drug.

Manufacture Standards & Regulation

Keeping Pace with the Plague

| Angus Stewart

Global regulators attended a virtual workshop on second generation COVID-19 vaccines – here’s what they talked about.

Manufacture Business Practice

COVID-19 and Beyond: Focusing on Patient-Centricity

Creating a patient-centric ecosystem in India.

Manufacture Bioprocessing - Upstream & Downstream

Eliminating Bioconjugation Roadblocks

| Charlie Huang

To speed up vaccine development, we need to assess our bioconjugation approaches.

Manufacture Packaging

The Value of a Pack

| Adrian Collins

As trials change and adapt, so too must clinical packaging.

Manufacture Small Molecules

Continuous Progress

| Doug Hausner

It's time to get off the fence and get on board with continuous manufacturing.

Manufacture Process Control

Sustainability in Bacterial Endotoxin Testing (BET) – A Holistic Approach to Conservation and Recombinant Technology

| Veronika S Wills

How a holistic approach to horseshoe crab sustainability will allow the industry to maintain stocks while protecting patients.

Discovery & Development Drug Discovery

Completing the Cell Therapy Revolution

| James Strachan

The question that’s on everyone’s lips: how can developers tackle solid tumors and bring cell therapy to millions?

Manufacture Bioprocessing - Upstream & Downstream

A Matter of Expression

| Joachim Klein, Julian Riba

Lonza and Cytena combine expertise to allow biotherapeutic manufacturers to benefit from the advantages of Pichia pastoris as an expression system.

Business & Regulation Analytical Science

AI Reunites Pharma with Mother Nature

| Stephanie Vine, Angus Stewart

Can AI facilitate a grand comeback for medicines sourced from Mother Nature?

Business & Regulation Biosimilars

What Lies Ahead for Biosimilars?

| Stephanie Vine

Sandoz’s Pierre Bourdage talks to us about biosimilars and how uptake can be boosted.

Business & Regulation Business Practice

Think of the Patients

| Stephanie Vine

GlaxoSmithKline’s Senior Vice President of US Oncology speaks about the pandemic and its impact on patients.

Business & Regulation Supply Chain

Getting it Right from the Start: Simulation Optimizes Supply Chain Planning for Clinical Trials

| Benedict Hirth

Clinical supply chains are inherently dynamic and ambiguous, contributing to a high degree of uncertainty.

Business & Regulation Profession

So, You Want to Become a CDMO…

| Sharon Johnson

Looking to pivot your business model to a CDMO service offering? Here’s what to keep in mind.

Business & Regulation Profession

Leadership Star

Sitting Down With… Andrew Moore, General Manager of Pfizer CentreOne.

Other issues of 2021