0121

In this issue, Upfront covers resilient supply chains, vaccine wars, and a gene therapy showing remarkable results in paralyzed animals. The focus of our cover feature is COVID-19; we gather experts from different sectors of the pharma industry to discuss how the pandemic has affected leadership and communication. Also in this issue: Ewoud van Tricht discusses analytical methods for vaccines, Alice Dunbabin talks about the benefits of biocatalysts; and Angela Myers and Michael Lehmicke explain how to standardize advanced therapy manufacture. We also have an interview with Sandy Macrae, CEO of Sangamo.

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Articles featured in this issue

Business & Regulation Standards & Regulation

Crisis-Ready: Building a Resilient Supply

02/02/2021 | Maryam Mahdi

Is the European Union better prepared for future healthcare crises?

Discovery & Development Dosage Forms

Crossing the Border

02/08/2021 | Stephanie Vine

How can we get macromolecules across the intestinal epithelial barrier?

Business & Regulation Standards & Regulation

Vaccine Wars: EU Member States Given Power to Block Certain Vaccine Exports

02/01/2021 | James Strachan

New EU “transparency” measures give member states the power to block vaccine exports if manufacturers can’t meet contractual obligations.

Discovery & Development Advanced Medicine

Paralyzed Mice Walk Again

01/26/2021 | James Strachan

Mice with severed spinal cords walk again after gene therapy.

Business & Regulation Contract Development Services

Keeping Your Nose in Front

02/01/2021 | Charles Evans

With the right partner to help you harness the many benefits, nasal delivery is not to be sniffed at.

Business & Regulation Business Practice

Big Pharma: Heal Thyself

02/09/2021 | Barry Silverstein

Pharma hasn’t always covered itself in glory – but as the world scrambles for viable COVID-19 interventions, it has a rare opportunity to rebrand.

Discovery & Development Formulation

The Inhalation Advantage

02/04/2021 | Sponsored by Vectura

Vectura has more than 20 years’ experience in helping customers bring inhaled medicines to the market.

Business & Regulation Business Practice

COVID-19: A Year of Unprecedented Change

03/01/2021 | Maryam Mahdi

What role have small molecules played in the fight against COVID-19?

Business & Regulation Advanced Medicine

Leadership in Times of Crisis

03/04/2021 | Stephanie Vine

Experts from our previous Power Lists discuss the challenges of leadership during these trying times.

Manufacture Bioprocessing - Upstream & Downstream

Capturing Value in Changing Times

02/04/2021 | Sponsored by Thermo Fisher Scientific

The increasing complexity of biologics raises significant manufacturing challenges – not least regarding cost control and downstream purification.

Discovery & Development COVID-19

Better Methods for Better Vaccines

01/18/2021 | Ewoud van Tricht

Ewoud van Tricht explores three novel methods that could streamline the development of adenovirus vaccines for COVID-19 at Janssen.

Manufacture Small Molecules

Are You a Bio-Catalytic Converter?

02/09/2021 | Alice Dunbabin

Biocatalysis is an increasingly attractive option in pharmaceutical synthesis.

Manufacture Standards & Regulation

How to Standardize Advanced Therapy Manufacture

02/20/2021 | James Strachan

Cell and gene therapy manufacturing technologies and methods are advancing rapidly, but can regulators keep up?

Discovery & Development Drug Delivery

Painting the Future of Drug Delivery

02/19/2021 | James Strachan

US Army combat veteran Luis Alvarez has developed a new drug delivery technology that can convert recombinant proteins into material-binding variants.