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December 2017 Issue of The Medicine Maker

Welcome to the last issue of 2017. This December issue features the annual Innovation Awards, showcasing the year’s 15 best drug development and manufacturing technologies. Upfront covers the road to a universal flu vaccine, continuous techniques for cell therapies, and more. In My View tackles the topics of drug attrition, revolutionizing drug development with bioprinting, and the impact of Brexit. And NextGen revolves around the challenges of creating specialty vaccines, and MVM-resistant CHO cell lines. In addition, we sit down with Richard Markus, Vice President of Global Development at Amgen, to talk about biosimilars.

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Articles featured in this issue

Manufacture Clinical Trials

Wise Words

| Stephanie Vine

Looking back on wise words from a year of Sitting Down With interviews.

Manufacture Bioprocessing - Single Use Systems

What's Next

Exploring the Future of Bioprocessing Together.

Manufacture Vaccines

Flu Fighters

The industry draws one step closer to creating a universal flu vaccine.

Manufacture Drug Delivery

Spray It Again, Sam

Could drug candidate screening and drug delivery benefit from vapor jet printing?

Manufacture Bioprocessing - Upstream & Downstream

Continuing the Trend

Cell therapy could be the next area to benefit from continuous production processes.

Manufacture Clinical Trials

Sharing Is Caring

Are pharma companies willling to open up and share their clinical trial data?

Business & Regulation Business Practice


Addressing the opioid crisis, 3D printing drug guidelines, and execution drugs…

Manufacture Clinical Trials

De-risking Drug Development

| Guy Webber

We need to face drug attrition to reduce the early-stage risk of drug development.

Manufacture Technology and Equipment

Think (Bio)Print

| Erik Gatenholm

Given the latest advances, bioprinting could play a large role in the future of medicine.

Business & Regulation Business Practice

Brexit Hits Home

| Steve Maginn

Can we predict the impact Brexit will have on UK life sciences?

Manufacture Technology and Equipment

Do AIs Dream of Electric R&D?

| Hui Cai

The technology around artificial intelligence is rapidly advancing – and it won’t be long before AI has a significant impact on pharma research and development.

Manufacture Packaging

Innovation Strikes Back

| Stephanie Vine

Our third annual Innovation Awards celebarate the most exciting developments and technologies of 2017.

Manufacture Analytical Science

The Innovators 2017

Meet the companies advancing pharmaceutical development and manufacture

Manufacture Vaccines

Fantastic Vaccines and Where to Find Them: Lessons Learned with Nima Farzan

| Nima Farzan

Public health groups have helped boost interest in the underserved market of specialty vaccines.

Manufacture Small Molecules

The Best Defense Is Good Science

| Kevin Kayser

Learn the story behind Centinel: the first Minute Virus of Mice-resistant CHO cell line.

Business & Regulation Biosimilars

Breaking Barriers to Biosimilars

| James Strachan

Sitting Down With… Richard Markus, Vice President of Global Development, Amgen, USA

Manufacture Analytical Science

How to Cultivate a Quality Mindset

| Fredrik Sundberg

Using precise and reliable analytical tools to ensure candidate molecule success.

Manufacture Bioprocessing - Upstream & Downstream

The Problem with Poloxamers-MS

| Sponsored by MilliporeSigma

Poloxamer 188 has become an essential component of cell culture media, but lot-to-lot variability has been a problem for many biopharma manufacturers.

Manufacture Technology and Equipment

The Transformation to Excellence-MS

| Sponsored by MilliporeSigma

How a customer focused mission to boost single-use assembly product quality and supply security led to the Mobius® MyWay Program and a manufacturing site transformation.

Manufacture Bioprocessing - Upstream & Downstream

Welcome to the Next Generation of Bioprocessing-MS

| Sponsored by MilliporeSigma

What is next generation bioprocessing? And how should it be implemented successfully?

Manufacture Bioprocessing - Upstream & Downstream

Facing the future-MS

| Jonathan Souquet, Merrilee Whitney

A supplier and a manufacturer share their views on why next generation bioprocessing is so important.

Manufacture Bioprocessing - Upstream & Downstream

The Connected Process-MS

| Michael Phillips, Janmeet Anant

Connecting processed is about running unit operations as a single unit, but how exactly is this achieved?

Manufacture Bioprocessing - Upstream & Downstream

Putting Single-Pass Tangential Flow Filtration into Place-MS

| Herb Lutz

Industry already has the technologies it needs for next generation bioprocessing - it just needs to deploy them effectively.

Manufacture Bioprocessing - Upstream & Downstream

Perfecting Perfusion-MS

| Delia Lyons

MilliporeSigma has developed a CHO cell perfusion medium specifically designed for untensified perfusion processes.

Manufacture Bioprocessing - Upstream & Downstream

New Horizons-MS

| Gorazd Hribar

A consortium funded by Horizon 2020 aims to bring biopharma manufacturing into the 21st century.

Manufacture Bioprocessing - Upstream & Downstream

Mastering Continuous Biomanufacturing-MS

| Rickey Lu

Interviewing Rickey Lu, Director of Manufacturing Technology Innovation, at AstraZeneca.

Other issues of 2017